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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-9-21
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pubmed:abstractText |
Angiogenesis gene therapy with human tissue kallikrein (hTK) has shown promise for ischemic disease. The present study was undertaken to (1) assess an optimal gene transfer modality, (2) clarify hTK angiogenic pathways, and (3) discount possible side effects.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AKT1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/NG-Nitroarginine Methyl Ester,
http://linkedlifedata.com/resource/pubmed/chemical/NOS3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoserine,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Kallikreins,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor...
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:ClergueMichelM,
pubmed-author:CondorelliGianluigiG,
pubmed-author:DesortesElisaE,
pubmed-author:EmanueliCostanzaC,
pubmed-author:FigueroaCarlos DCD,
pubmed-author:GadauSergioS,
pubmed-author:MadedduPaoloP,
pubmed-author:MeloniMarcoM,
pubmed-author:SalisMaria BMB,
pubmed-author:SilvestreJean-SebastienJS,
pubmed-author:Van LinthoutSophieS
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pubmed:issnType |
Electronic
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pubmed:day |
21
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1638-44
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15364809-Adenoviridae,
pubmed-meshheading:15364809-Animals,
pubmed-meshheading:15364809-Blotting, Western,
pubmed-meshheading:15364809-Cell Division,
pubmed-meshheading:15364809-Endothelial Cells,
pubmed-meshheading:15364809-Endothelium, Vascular,
pubmed-meshheading:15364809-Enzyme Induction,
pubmed-meshheading:15364809-Exudates and Transudates,
pubmed-meshheading:15364809-Genes, Dominant,
pubmed-meshheading:15364809-Genetic Vectors,
pubmed-meshheading:15364809-Humans,
pubmed-meshheading:15364809-Mice,
pubmed-meshheading:15364809-Microcirculation,
pubmed-meshheading:15364809-Muscle, Skeletal,
pubmed-meshheading:15364809-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:15364809-Neovascularization, Physiologic,
pubmed-meshheading:15364809-Nitric Oxide Synthase,
pubmed-meshheading:15364809-Nitric Oxide Synthase Type II,
pubmed-meshheading:15364809-Nitric Oxide Synthase Type III,
pubmed-meshheading:15364809-Phosphorylation,
pubmed-meshheading:15364809-Phosphoserine,
pubmed-meshheading:15364809-Polymerase Chain Reaction,
pubmed-meshheading:15364809-Protein Processing, Post-Translational,
pubmed-meshheading:15364809-Protein-Serine-Threonine Kinases,
pubmed-meshheading:15364809-Proto-Oncogene Proteins,
pubmed-meshheading:15364809-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:15364809-RNA, Messenger,
pubmed-meshheading:15364809-Tissue Kallikreins,
pubmed-meshheading:15364809-Transduction, Genetic,
pubmed-meshheading:15364809-Vascular Endothelial Growth Factor A,
pubmed-meshheading:15364809-Vascular Endothelial Growth Factor Receptor-2
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pubmed:year |
2004
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pubmed:articleTitle |
Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer.
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pubmed:affiliation |
Experimental Medicine and Gene Therapy Section, INBB, Alghero, Italy. emanueli@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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