Linked Life Data

15364600

Source:http://linkedlifedata.com/resource/pubmed/id/15364600

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-9-14
pubmed:abstractText
The acute toxicity of azodrin (monocrotophos, an organophosphorus insecticide) was determined on a soil organism, Eisenia foetida. The median lethal concentrations (LC50) were derived from a 48-h paper contact test and from artificial soil tests. The LC50 of azodrin in the paper contact test was 0.46 +/- 0.1 microg cm(-2) (23 +/- 6 mg L(-1)) and those in the 7- and 14-day artificial soil tests were 171 +/- 21 and 132 +/- 20 mg kg(-1), respectively. The neurotoxic potentiality of azodrin was assessed by using a marker enzyme, acetylcholinesterase (AChE; EC 3.1.1.7) in both in vitro and in vivo experiments. The progressive signs of morphological destruction are correlated with percentage inhibition of AChE in the in vivo experiments. The kinetics of AChE activity in the presence and absence of azodrin indicated that the toxicant is competitive in nature. This study demonstrated that azodrin causes concentration-dependent changes in the morphology and AChE activity of the earthworm E. foetida.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0013-9351
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Toxicity of azodrin on the morphology and acetylcholinesterase activity of the earthworm Eisenia foetida.
pubmed:affiliation
Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500-007, India. jv@iict.res.in
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't