Source:http://linkedlifedata.com/resource/pubmed/id/15364437
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
29-30
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pubmed:dateCreated |
2004-9-14
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pubmed:abstractText |
A randomized study of injecting drug users in a Danish prison comparing vaccination at 0, 1 and 3 weeks with the 0, 1 and 6 months schedule (20microg Engerix B i.m.) was conducted. Due to a low participation rate, a second nonrandomized study was conducted in Estonia where all prisoners were vaccinated with the short schedule. In the randomized study, the compliance with three doses was 63% (12/19) in the 3-week schedule compared to 20% (3/15) in the 6-month schedule (P = 0.017). In the nonrandomized study, the compliance was 81% (457/566) and the seroprotection rate at month 7 was 67% (97/145), resulting in protection of 54% of the population at risk. This was significantly higher than the estimated 34-42% protection that would have been achieved with the 6-month schedule.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0264-410X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3897-901
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15364437-Adult,
pubmed-meshheading:15364437-Aged,
pubmed-meshheading:15364437-Denmark,
pubmed-meshheading:15364437-Estonia,
pubmed-meshheading:15364437-Female,
pubmed-meshheading:15364437-Hepatitis B,
pubmed-meshheading:15364437-Hepatitis B Antibodies,
pubmed-meshheading:15364437-Hepatitis B Vaccines,
pubmed-meshheading:15364437-Humans,
pubmed-meshheading:15364437-Immunization Schedule,
pubmed-meshheading:15364437-Male,
pubmed-meshheading:15364437-Middle Aged,
pubmed-meshheading:15364437-Prisoners,
pubmed-meshheading:15364437-Substance Abuse, Intravenous,
pubmed-meshheading:15364437-Vaccination,
pubmed-meshheading:15364437-Vaccines, Synthetic
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pubmed:year |
2004
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pubmed:articleTitle |
Hepatitis B vaccination in prison with a 3-week schedule is more efficient than the standard 6-month schedule.
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pubmed:affiliation |
Department of Medicine C, Section of Infectious Diseases, Odense University Hospital, DK 5000 Odense C, Denmark. peer.christensen@dadlnet.dk
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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