Source:http://linkedlifedata.com/resource/pubmed/id/15359893
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2004-9-13
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pubmed:abstractText |
Haemophilus influenzae type b (Hib) is the most frequent pathogen of bacterial meningitis in Japanese children. The prevalence of beta-lactamase-negative ampicillin-resistant (BLNAR) Hib strain has been increasing in recent years. Furthermore, antibiotic activities of cefotaxime (CTX) and ceftriaxone (CTRX) have decreased against some of those BLNAR strains. We report a case of one-year-old boy who suffered from meningitis caused by BLNAR Hib. The MICs of CTX and CTRX for the strain isolated from cerebrospinal fluid was 1.0 and 0.5 microg/ml, respectively. The patient was administered high-dose CTRX (150 mg/kg/day) and recovered completely without any sequela. The high-dose CTRX administration may be a considerable choice of the treatment of BLNAR meningitis.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0387-5911
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
604-8
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pubmed:dateRevised |
2008-12-16
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pubmed:meshHeading |
pubmed-meshheading:15359893-Ampicillin Resistance,
pubmed-meshheading:15359893-Anti-Bacterial Agents,
pubmed-meshheading:15359893-Ceftriaxone,
pubmed-meshheading:15359893-Haemophilus influenzae type b,
pubmed-meshheading:15359893-Humans,
pubmed-meshheading:15359893-Infant,
pubmed-meshheading:15359893-Male,
pubmed-meshheading:15359893-Meningitis, Haemophilus,
pubmed-meshheading:15359893-beta-Lactamases
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pubmed:year |
2004
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pubmed:articleTitle |
[Successful treatment of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b meningitis with high-dose ceftriaxone administration].
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pubmed:affiliation |
Division of Infectious Diseases, Chiba Children's Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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