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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2004-9-14
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pubmed:abstractText |
Nitric oxide (NO) is an endothelial mediator that regulates vascular smooth muscle tone, but it may exert its cardiovascular action also by modulating the autonomic control of vasomotor tone. We assessed the effect of simultaneous inhibition of both endothelial (eNOS) and neuronal (nNOS) NO synthase isoforms on myocardial blood flow (MBF) and coronary flow reserve (CFR) in volunteers and in (denervated) transplant recipients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine,
http://linkedlifedata.com/resource/pubmed/chemical/NOS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/NOS3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/omega-N-Methylarginine
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1431-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15353503-Adenosine,
pubmed-meshheading:15353503-Adult,
pubmed-meshheading:15353503-Autonomic Denervation,
pubmed-meshheading:15353503-Blood Pressure,
pubmed-meshheading:15353503-Coronary Circulation,
pubmed-meshheading:15353503-Dose-Response Relationship, Drug,
pubmed-meshheading:15353503-Heart,
pubmed-meshheading:15353503-Heart Rate,
pubmed-meshheading:15353503-Heart Transplantation,
pubmed-meshheading:15353503-Humans,
pubmed-meshheading:15353503-Hyperemia,
pubmed-meshheading:15353503-Male,
pubmed-meshheading:15353503-Middle Aged,
pubmed-meshheading:15353503-Nerve Tissue Proteins,
pubmed-meshheading:15353503-Nitric Oxide,
pubmed-meshheading:15353503-Nitric Oxide Synthase,
pubmed-meshheading:15353503-Nitric Oxide Synthase Type I,
pubmed-meshheading:15353503-Nitric Oxide Synthase Type III,
pubmed-meshheading:15353503-Positron-Emission Tomography,
pubmed-meshheading:15353503-Postoperative Period,
pubmed-meshheading:15353503-Rest,
pubmed-meshheading:15353503-Vasoconstriction,
pubmed-meshheading:15353503-omega-N-Methylarginine
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pubmed:year |
2004
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pubmed:articleTitle |
Systemic inhibition of nitric oxide synthase unmasks neural constraint of maximal myocardial blood flow in humans.
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pubmed:affiliation |
MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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