Linked Life Data

15351433

Source:http://linkedlifedata.com/resource/pubmed/id/15351433

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-9-7
pubmed:abstractText
We studied the distribution of Na(+)/HCO(3)(-) cotransporters (NBC) and Na(+)/H(+) exchanger type 3 (NHE3) in the laryngeal nerve by immunohistochemistry to elucidate the spatial relationship of pH regulation system in the peripheral nerves. The nervous components, i.e., the nerve cells in the nodose and local ganglia and nerve fibers, were immunoreactive for NBC. Glial components such as Schwann cells and satellite cells surrounding nerve fibers and nerve cell bodies were also immunoreactive for NBC in most cases, while the cells comprising the perineurium and endoneurium were immunoreactive for NHE3. These results suggest that NBC-dependent pH regulation systems are present in the laryngeal nerve. Whereas, NHE3 may regulate extracellular pH rather than intracellular pH. In conclusion, spatial relationship of NBC and NHE3 in the laryngeal nerve would be important for pH regulation. Perineural lymph may have key role for acid-induced modulation of axons and Schwann cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
368
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Distribution of pH regulators in the rat laryngeal nerve: the spatial relationship between Na(+)/HCO(3)(-) cotransporters and Na(+)/H(+) exchanger type 3.
pubmed:affiliation
Laboratory of Veterinary Anatomy, Faculty of Agriculture, Morioka, Iwate 020-8550, Japan. yyoshio@iwate-u.ac.jp
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't