Source:http://linkedlifedata.com/resource/pubmed/id/15349117
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2004-9-6
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pubmed:abstractText |
Pancreatic duct cells (PDCs) are responsible for bicarbonate production by the pancreas. The trypsin-sensitive protease-activated receptor (PAR-2), also known as the trypsin receptor, is highly expressed in the pancreatic duct system and has been shown to regulate PDC ion transport. The possible role of this receptor on bicarbonate secretion, the central function of duct cells, is unknown. We hypothesize that PAR-2 may regulate pancreatic bicarbonate secretion during times of inappropriate pancreatic enzyme activation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0039-6060
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
669-76
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15349117-Animals,
pubmed-meshheading:15349117-Bicarbonates,
pubmed-meshheading:15349117-Cattle,
pubmed-meshheading:15349117-Cells, Cultured,
pubmed-meshheading:15349117-Pancreatic Ducts,
pubmed-meshheading:15349117-Receptor, PAR-2,
pubmed-meshheading:15349117-Serine Endopeptidases,
pubmed-meshheading:15349117-Trypsin
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pubmed:year |
2004
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pubmed:articleTitle |
Protease-activated receptor-2 regulates bicarbonate secretion by pancreatic duct cells in vitro.
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pubmed:affiliation |
Department of Surgery, University of Medicine and Dentistry of New Jersey - New Jersey Medical School, Newark, NJ, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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