Source:http://linkedlifedata.com/resource/pubmed/id/15346769
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-9-6
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pubmed:abstractText |
SGT1.2, a novel splice variant of Homo sapiens SGT1 was isolated from a human fetal brain cDNA library. This cDNA is 1404 bp and contains an open reading frame from 68 to 1165 encoding a putative protein of 365 amino acids (SGT1.2) that share 90% identities to Homo sapiens SGT1, suppressor of G2 allele of SKP1 at protein level. RPS-BLAST searching revealed that SGT1.2 have a TPR domain, a p23 domain, a SGS domain and a CS domain. According to the search of the human genome database, SGT1.2 was mapped to human chromosome 13q14.13. Reversed transcription-polymerase chain reaction analysis indicated that it widely expressed in human adult tissues.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1042-5179
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
140-3
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15346769-Alternative Splicing,
pubmed-meshheading:15346769-Amino Acid Sequence,
pubmed-meshheading:15346769-Animals,
pubmed-meshheading:15346769-Base Sequence,
pubmed-meshheading:15346769-Cell Cycle Proteins,
pubmed-meshheading:15346769-Cloning, Molecular,
pubmed-meshheading:15346769-DNA, Complementary,
pubmed-meshheading:15346769-Genetic Variation,
pubmed-meshheading:15346769-Hominidae,
pubmed-meshheading:15346769-Humans,
pubmed-meshheading:15346769-Molecular Sequence Data,
pubmed-meshheading:15346769-Sequence Alignment,
pubmed-meshheading:15346769-Sequence Homology, Amino Acid
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pubmed:year |
2004
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pubmed:articleTitle |
Molecular cloning and characterization of SGT1.2, a novel splice variant of Homo sapiens SGT1.
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pubmed:affiliation |
a State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, P. R. China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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