Linked Life Data

1534375

Source:http://linkedlifedata.com/resource/pubmed/id/1534375

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-7-1
pubmed:abstractText
Peripheral blood cytotoxic lymphocytes, including gamma delta+ T cells, natural killer (NK) cells, and CD56+ T lymphocytes were investigated by using 2-color flow cytometry in patients with Behçet's disease. The percentage of circulating gamma delta+ T cells among total lymphocytes or among total T cells was significantly increased in patients with Behçet's disease, compared to healthy controls. An increase in circulating gamma delta+ T cells was related to mucocutaneous lesions, but not the HLA-B51. Among gamma delta+ T cells, the number of CD8+ or CD56+ subset was significantly increased in patients with Behçet's disease. Moreover, significant increases of peripheral blood NK cells (CD16+CD56+CD3-, CD2+CD3-, CD8dim+CD3-) and CD56+ T lymphocytes were also observed. Our data suggest that increased circulating gamma delta+ T cells and NK cells may play an important role in the pathogenesis of Behçet's disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
588-92
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Increased peripheral blood gamma delta+ T cells and natural killer cells in Behçet's disease.
pubmed:affiliation
Department of Rheumatology, St. Marianna University School of Medicine, Kawasaki, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't