| pubmed-article:1534311 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1534311 | lifeskim:mentions | umls-concept:C0004096 | lld:lifeskim |
| pubmed-article:1534311 | lifeskim:mentions | umls-concept:C0392707 | lld:lifeskim |
| pubmed-article:1534311 | lifeskim:mentions | umls-concept:C0108779 | lld:lifeskim |
| pubmed-article:1534311 | lifeskim:mentions | umls-concept:C1334114 | lld:lifeskim |
| pubmed-article:1534311 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1534311 | pubmed:dateCreated | 1992-7-2 | lld:pubmed |
| pubmed-article:1534311 | pubmed:abstractText | In an attempt to identify the phenotype of the CD25+ cells previously demonstrated in late-phase allergic reactions in skin and nasal mucosa, and in the bronchial mucosa in atopic asthma we have investigated the co-expression of CD3 and CD25 using double immunofluorescent staining. Fluorescein isothiocyanate (FITC) conjugated anti-CD3 monoclonal antibody and a biotinylated anti-CD25 monoclonal antibody (which was later developed with Texas Red streptavidin) were applied simultaneously to cryostat sections or cytospins of freshly prepared samples. Skin and nasal biopsies were from antigen-induced late-phase reactions, and bronchial biopsies and cytospins of bronchoalveolar lavage cells were from subjects with moderate atopic asthma. Four to 14% of CD3+ cells in these tissues were CD25+ and 61-100% of CD25+ cells also expressed CD3. However, CD25 was also expressed on non-CD3+ cells, assumed to be non-T cells. These results were comparable to that observed with a positive control of a tuberculin-challenged skin biopsy. Thus the majority of cells expressing CD25 in various types of atopic allergic inflammation in man were T lymphocytes. | lld:pubmed |
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| pubmed-article:1534311 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1534311 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1534311 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1534311 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1534311 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1534311 | pubmed:issn | 0019-2805 | lld:pubmed |
| pubmed-article:1534311 | pubmed:author | pubmed-author:KayA BAB | lld:pubmed |
| pubmed-article:1534311 | pubmed:author | pubmed-author:RobinsonD SDS | lld:pubmed |
| pubmed-article:1534311 | pubmed:author | pubmed-author:DurhamS RSR | lld:pubmed |
| pubmed-article:1534311 | pubmed:author | pubmed-author:BarkansJJ | lld:pubmed |
| pubmed-article:1534311 | pubmed:author | pubmed-author:HamidQQ | lld:pubmed |
| pubmed-article:1534311 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1534311 | pubmed:volume | 75 | lld:pubmed |
| pubmed-article:1534311 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1534311 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1534311 | pubmed:pagination | 659-63 | lld:pubmed |
| pubmed-article:1534311 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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| pubmed-article:1534311 | pubmed:meshHeading | pubmed-meshheading:1534311-... | lld:pubmed |
| pubmed-article:1534311 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1534311 | pubmed:articleTitle | Co-expression of CD25 and CD3 in atopic allergy and asthma. | lld:pubmed |
| pubmed-article:1534311 | pubmed:affiliation | Department of Allergy and Clinical Immunology, National Heart and Lung Institute, London, U.K. | lld:pubmed |
| pubmed-article:1534311 | pubmed:publicationType | Journal Article | lld:pubmed |
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