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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-9-2
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pubmed:abstractText |
Although earlier studies have suggested that early continuous airway positive pressure (CPAP) may be beneficial in reducing ventilator dependence and subsequent chronic lung disease in the extremely low birth weight (ELBW) infant, the time of initiation of CPAP has varied, and there are no prospective studies of infants who have received CPAP or positive end-expiratory pressure (PEEP) from initial resuscitation in the delivery room (DR). Current practice for the ELBW infant includes early intubation and the administration of prophylactic surfactant, often in the DR. The feasibility of initiating CPAP in the DR and continuing this therapy without intubation for surfactant has never been determined prospectively in a population of ELBW infants. This study was designed to determine the feasibility of randomizing ELBW infants of <28 weeks' gestation to CPAP/PEEP or no CPAP/PEEP during resuscitation immediately after delivery, avoiding routine DR intubation for surfactant administration, initiating CPAP on neonatal intensive care unit (NICU) admission, and assessing compliance with subsequent intubation criteria.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/M01 RR00070,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR00750,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR00997,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR01032,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR02172,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR02635,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR06022,
http://linkedlifedata.com/resource/pubmed/grant/M01 RR08084,
http://linkedlifedata.com/resource/pubmed/grant/U01 HD36790,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21364,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21373,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21385,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21397,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD21415,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27851,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27853,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27856,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27871,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27880,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27881,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD27904,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD34167,
http://linkedlifedata.com/resource/pubmed/grant/U10 HD34216
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1098-4275
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
651-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15342835-Bronchopulmonary Dysplasia,
pubmed-meshheading:15342835-Continuous Positive Airway Pressure,
pubmed-meshheading:15342835-Delivery Rooms,
pubmed-meshheading:15342835-Feasibility Studies,
pubmed-meshheading:15342835-Humans,
pubmed-meshheading:15342835-Infant, Newborn,
pubmed-meshheading:15342835-Infant, Premature,
pubmed-meshheading:15342835-Infant, Very Low Birth Weight,
pubmed-meshheading:15342835-Intubation, Intratracheal,
pubmed-meshheading:15342835-Oxygen Inhalation Therapy,
pubmed-meshheading:15342835-Positive-Pressure Respiration,
pubmed-meshheading:15342835-Resuscitation
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pubmed:year |
2004
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pubmed:articleTitle |
Delivery room continuous positive airway pressure/positive end-expiratory pressure in extremely low birth weight infants: a feasibility trial.
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pubmed:affiliation |
Department of Pediatrics, University of California, 200 W Arbor Dr, 8774, San Diego, CA 92103-8774, USA. nfiner@ucsd.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Multicenter Study
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