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rdf:type |
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lifeskim:mentions |
umls-concept:C0006711,
umls-concept:C0026336,
umls-concept:C0043240,
umls-concept:C0086466,
umls-concept:C0237798,
umls-concept:C1272883,
umls-concept:C1272936,
umls-concept:C1321899,
umls-concept:C1445578,
umls-concept:C1533685,
umls-concept:C1705822
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pubmed:issue |
9
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pubmed:dateCreated |
2004-9-2
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pubmed:abstractText |
In recent clinical trials demonstrating the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2) for the acceleration of bone-healing, investigators used carriers requiring open surgery for administration. In this study, we used a nonhuman primate fibular osteotomy model to evaluate injectable rhBMP-2/carrier formulations that can be administered in closed fractures.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0021-9355
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
86-A
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1961-72
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pubmed:dateRevised |
2010-10-25
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pubmed:meshHeading |
pubmed-meshheading:15342759-Animals,
pubmed-meshheading:15342759-Biomechanics,
pubmed-meshheading:15342759-Bone Morphogenetic Protein 2,
pubmed-meshheading:15342759-Bone Morphogenetic Proteins,
pubmed-meshheading:15342759-Calcium Phosphates,
pubmed-meshheading:15342759-Drug Carriers,
pubmed-meshheading:15342759-Fracture Healing,
pubmed-meshheading:15342759-Fractures, Bone,
pubmed-meshheading:15342759-Injections,
pubmed-meshheading:15342759-Macaca fascicularis,
pubmed-meshheading:15342759-Male,
pubmed-meshheading:15342759-Ointments,
pubmed-meshheading:15342759-Osteotomy,
pubmed-meshheading:15342759-Time Factors,
pubmed-meshheading:15342759-Transforming Growth Factor beta
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pubmed:year |
2004
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pubmed:articleTitle |
Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model.
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pubmed:affiliation |
Women's Health and Bone, Wyeth Discovery Research, 200 Cambridge Park Drive, Cambridge, MA 02140, USA. hseeherman@wyeth.com
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pubmed:publicationType |
Journal Article
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