Source:http://linkedlifedata.com/resource/pubmed/id/15334485
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
2004-8-30
|
pubmed:abstractText |
Osteopontin (OPN) is a secreted glycoprotein involved in a range of physiologic processes, including inflammation, immunity mediated by Th1 cells, and bone remodeling. It is expressed in the joints of rheumatoid arthritis patients and has been the subject of conflicting reports concerning its role in arthritis induced by antibodies against type II collagen. This study assessed the role of OPN in the K/BxN serum-transfer model of autoantibody-induced arthritis.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0004-3591
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2685-94
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:15334485-Animals,
pubmed-meshheading:15334485-Arthritis,
pubmed-meshheading:15334485-Autoantibodies,
pubmed-meshheading:15334485-Autoimmune Diseases,
pubmed-meshheading:15334485-Bone and Bones,
pubmed-meshheading:15334485-Cartilage,
pubmed-meshheading:15334485-Inflammation,
pubmed-meshheading:15334485-Mice,
pubmed-meshheading:15334485-Mice, Inbred C57BL,
pubmed-meshheading:15334485-Mice, Knockout,
pubmed-meshheading:15334485-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:15334485-Osteopontin,
pubmed-meshheading:15334485-Sialoglycoproteins,
pubmed-meshheading:15334485-Transcription, Genetic
|
pubmed:year |
2004
|
pubmed:articleTitle |
Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis.
|
pubmed:affiliation |
Joslin Diabetes Center, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts 02215, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|