Linked Life Data

15332353

Source:http://linkedlifedata.com/resource/pubmed/id/15332353

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-8-30
pubmed:abstractText
Researchers have turned their attention to the effects of alcohol consumption on breastfeeding, with significant negative findings concerning both the mother and the newborn. This study is a meta-analysis of the principle research performed in the last decade that was concerned with lactation and alcohol. Results from experimental and human subject research has shown that effects of alcohol include: behavioural changes, reduced milk and luteinising hormone production, with increased fat content, reduced lactose content. Increased lipogenesis and increased activity of lipoprotein and hormone-sensitive lipase, structural alterations in the epithelial cells of the breast and abnormal casein production, reduced oxytocin and prolactin production with subsequent reduced milk ejection, and reduced weight and protein content of the breast. Reduction in food consumption, body weight, growth and development and hepatic glycogen, serum glucose, amino-acids, insulin, glycerol, fatty acids and urea, and an increase in serum acetoacetic acid is seen in newborn children that were breastfed by animals with a high intake of alcohol during pregnancy or the puerperal period. Alcohol consumption during lactation caused a reduction in liver weight and triglyceride, protein, DNA and lipid content, in the newborns. Serum changes included a reduction in protein, triglyceride, cholesterol, fatty acid and glycerol level with an increase in beta-hydroxybutirate levels. Changes also included alterations in the motor system and behaviour. Further studies are needed to determine, with confidence, the minimum level of alcohol consumption that can provoke pathological effects in both the mother and the child.
pubmed:language
por
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0004-0622
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-35
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[Lactation and alcohol: clinical and nutritional effects].
pubmed:affiliation
Laboratório de Nutrição Experimental, Departamento de Nutrição, Centro de Ciências da Saúde, Universidade Federal de Pernambuco.
pubmed:publicationType
Journal Article, English Abstract, Review, Meta-Analysis