Three-dimensional (3-D) culture systems that simulate the tumor extracellular microenvironment may be appropriate to test cancer cell potential for invasion and tumor cell sensitivity to anticancer drugs.
Oncology and Molecular Endocrinology Research Center, CHUL's Research Center, CHUQ, 2705 boul. Laurier, Quebec City, Québec G1V 4G2, Canada. Charles.doillon@crchul.ulaval.ca