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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-8-26
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pubmed:abstractText |
Skeletal muscle failure and wasting are manifestations of sepsis in humans that leads to serious and prolonged complications. The authors investigated the role of the major proinflammatory and antiinflammatory pathways, namely the inducible isoforms cyclooxygenase (COX-2) and heme oxygenase (HO-1), and the ubiquitin proteolytic pathway in skeletal muscle of septic patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Heme Oxygenase (Decyclizing),
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/Ubiquitin
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
583-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15329582-Adult,
pubmed-meshheading:15329582-Aged,
pubmed-meshheading:15329582-Aged, 80 and over,
pubmed-meshheading:15329582-Blotting, Western,
pubmed-meshheading:15329582-Cyclooxygenase 1,
pubmed-meshheading:15329582-Cyclooxygenase 2,
pubmed-meshheading:15329582-Endopeptidases,
pubmed-meshheading:15329582-Enzyme Induction,
pubmed-meshheading:15329582-Female,
pubmed-meshheading:15329582-Heme Oxygenase (Decyclizing),
pubmed-meshheading:15329582-Humans,
pubmed-meshheading:15329582-Immunohistochemistry,
pubmed-meshheading:15329582-Isoenzymes,
pubmed-meshheading:15329582-Male,
pubmed-meshheading:15329582-Membrane Proteins,
pubmed-meshheading:15329582-Middle Aged,
pubmed-meshheading:15329582-Muscular Diseases,
pubmed-meshheading:15329582-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:15329582-Sepsis,
pubmed-meshheading:15329582-Ubiquitin
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pubmed:year |
2004
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pubmed:articleTitle |
Human septic myopathy: induction of cyclooxygenase, heme oxygenase and activation of the ubiquitin proteolytic pathway.
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pubmed:affiliation |
Department of Anesthesiology and Critical Care Medicine, Institut National de la Santé et de la Recherche Médicale (INSERM) U572, Paris, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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