| pubmed-article:15326303 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0003518 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0085211 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0324846 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0553257 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0332285 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0162768 | lld:lifeskim |
| pubmed-article:15326303 | lifeskim:mentions | umls-concept:C0443288 | lld:lifeskim |
| pubmed-article:15326303 | pubmed:issue | 36 | lld:pubmed |
| pubmed-article:15326303 | pubmed:dateCreated | 2004-9-8 | lld:pubmed |
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| pubmed-article:15326303 | pubmed:abstractText | Lv1 restriction of HIV-1 in the cells of Old World monkeys is associated with the expression of the Trim5 gene. Uniquely, in owl monkey kidney cells, HIV-1 restriction is dependent on the ability of incoming viral capsid protein to bind cyclophilin A (CypA). Cloning of the owl monkey Trim5 gene now reveals the presence of an inserted CypA pseudogene within intron 7 of the Trim5 gene. This insertion results in the formation of a chimeric Trim5-CypA transcript. Transfer of a cDNA corresponding to this transcript into human cells confers cyclosporin A-sensitive resistance to HIV-1 infection. The restriction factor appears to be a chimeric protein created by retrotransposon-mediated exon shuffling. | lld:pubmed |
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| pubmed-article:15326303 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15326303 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15326303 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15326303 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15326303 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:15326303 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:15326303 | pubmed:author | pubmed-author:NisoleSébasti... | lld:pubmed |
| pubmed-article:15326303 | pubmed:author | pubmed-author:StoyeJonathan... | lld:pubmed |
| pubmed-article:15326303 | pubmed:author | pubmed-author:YapMelvyn WMW | lld:pubmed |
| pubmed-article:15326303 | pubmed:author | pubmed-author:LynchClareC | lld:pubmed |
| pubmed-article:15326303 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15326303 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:15326303 | pubmed:volume | 101 | lld:pubmed |
| pubmed-article:15326303 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15326303 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15326303 | pubmed:pagination | 13324-8 | lld:pubmed |
| pubmed-article:15326303 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
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| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:meshHeading | pubmed-meshheading:15326303... | lld:pubmed |
| pubmed-article:15326303 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15326303 | pubmed:articleTitle | A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1. | lld:pubmed |
| pubmed-article:15326303 | pubmed:affiliation | Division of Virology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom. | lld:pubmed |
| pubmed-article:15326303 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15326303 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
