Source:http://linkedlifedata.com/resource/pubmed/id/15322634
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-8-23
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pubmed:abstractText |
One of the main opportunistic fungal infections amongst immunocompromised individuals is oral candidosis, which has been found in up to 90% of human immunodeficiency virus (HIV)-infected patients. This study employed yeasts isolated from the saliva and oral cavities of 114 HIV-infected patients living in Campinas, São Paulo. Of the isolates, 57.8% were identified as Candida albicans and 42.1% as non-C. albicans. The latter isolates were subsequently identified as C. krusei (7.5%), C. lusitaniae (5.2%), C. tropicalis (4.6%), C. parapsilosis (4.6%), C. glabrata (2.8%), C. kefyr (1.7%), C. guilliermondii (1.7%), C. intermedia (1.1%), C. norvegensis (0.5%), and Rhodotorula rubra (1.7%). Susceptibility of the isolates to amphotericin B, fluconazole, miconazole, and itraconazole was also determined by a microdilution method adopted by the National Committee for Clinical Laboratory Standards. The isolates demonstrated various susceptibilities to the antifungal agents. In particular 29 C. albicans and 13 non-C. albicans isolates showed low susceptibility to FLCZ (> 64 micro g/ml). This study revealed huge diversity of Candida species, in particular the increasing emergence of non-C. albicans associated with the oral flora of HIV-infected patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0074-0276
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
425-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15322634-AIDS-Related Opportunistic Infections,
pubmed-meshheading:15322634-Antifungal Agents,
pubmed-meshheading:15322634-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:15322634-Brazil,
pubmed-meshheading:15322634-Candida,
pubmed-meshheading:15322634-Candidiasis, Oral,
pubmed-meshheading:15322634-Case-Control Studies,
pubmed-meshheading:15322634-Female,
pubmed-meshheading:15322634-HIV Infections,
pubmed-meshheading:15322634-Humans,
pubmed-meshheading:15322634-Male,
pubmed-meshheading:15322634-Microbial Sensitivity Tests
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pubmed:year |
2004
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pubmed:articleTitle |
Oral Candida flora from Brazilian human immunodeficiency virus-infected patients in the highly active antiretroviral therapy era.
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pubmed:affiliation |
Departamento de Patologia Oral, Faculdade de Odontologia de Piracicaba, Piracicaba, SP, Brazil. nadjarm@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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