Linked Life Data

15319499

Source:http://linkedlifedata.com/resource/pubmed/id/15319499

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-8-20
pubmed:abstractText
Lumbar spine body mineral density (BMD) was measured in 123 children (65 male, 58 female) suffering from inflammatory bowel disease (IBD) (82 Crohn's disease, 41 ulcerative colitis) and in 46 children (25 male, 21 female) without any history of bone disease. Results in normal children showed that densitometer-derived reference values overestimated spine BMD, particularly for young children, such that the reported mean Z-scores for normal 10-yr-old children were -0.83 for males and -0.72 for females. For children with Crohn's disease, the lumbar spine BMD was further reduced (Z-score = -1.44 for males, Z-score = -1.37 for females). For children with ulcerative colitis, the lumbar spine BMD was similar to that of normal children (Z-score = -0.93 for males, Z-score = -0.56 for females). There was no statistically significant reduction in average spine BMD Z-scores during follow-up periods ranging from 1.7 to 8.7 yr. When growth patterns were examined in individual children, six patients (three Crohn's disease, three ulcerative colitis) were identified as losing spine BMD with respect to their baseline value and their expected pattern of BMD increase associated with normal growth. The children suffering from IBD who, most likely, will not maintain expected growth-related increases in spine BMD are those who are male, relatively young at diagnosis, and unlikely to be taking immunosuppressants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1094-6950
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
290-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Lumbar spine bone mineral density at diagnosis and during follow-up in children with IBD.
pubmed:affiliation
McMaster Children's Hospital and Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
pubmed:publicationType
Journal Article