Linked Life Data

15316424

Source:http://linkedlifedata.com/resource/pubmed/id/15316424

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2004-8-18
pubmed:abstractText
Refractory ulcerative colitis that fails conventional intense medical treatment often leads to colectomy. Although ciclosporin and infliximab may avert colectomy in certain cases, these treatments come with substantial toxicity and may only act as a bridge to avert emergency surgery. Granulocyte monocyte/macrophage adsorption apheresis is a new treatment and has shown efficacy for refractory colitis in up to 80% of cases in a Japanese study and is apparently only associated with negligible side effects. We report a case of severe refractory proctitis destined for colectomy effectively treated with granulocyte monocyte/macrophage adsorption apheresis. After two of five sessions the patient achieved full clinical remission, which has been sustained with the addition of azathioprine for more than 1 year.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0954-691X
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
943-5
pubmed:dateRevised
2009-10-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Granulocyte, macrophage, monocyte apheresis for refractory ulcerative proctitis.
pubmed:affiliation
Department of Gastroenterology, Guy's School of Medicine, London SE5 9PJ, UK. purushothaman.premchand@gstt.nhs.uk
pubmed:publicationType
Journal Article, Case Reports