Source:http://linkedlifedata.com/resource/pubmed/id/15315451
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
33
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pubmed:dateCreated |
2004-8-18
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pubmed:abstractText |
Using a new approach based on the NMR spectroscopic analysis of the entire, unpurified spider venom, we identified a family of unusual sulfated nucleoside derivatives from the venom of the hobo spider, Tegenaria agrestis. These compounds are ribonucleoside mono- and disulfates derived from guanosine and xanthosine, some of which are glycosylated, bearing one or two D-fucose units. The use of NMR spectroscopy to characterize the unfractionated venom was central to the discovery of this heretofore overlooked class of venom components.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0002-7863
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
10364-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15315451-Animals,
pubmed-meshheading:15315451-Carbohydrate Conformation,
pubmed-meshheading:15315451-Carbohydrate Sequence,
pubmed-meshheading:15315451-Molecular Sequence Data,
pubmed-meshheading:15315451-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:15315451-Nucleosides,
pubmed-meshheading:15315451-Spider Venoms,
pubmed-meshheading:15315451-Spiders,
pubmed-meshheading:15315451-Sulfates
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pubmed:year |
2004
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pubmed:articleTitle |
A new approach to natural products discovery exemplified by the identification of sulfated nucleosides in spider venom.
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pubmed:affiliation |
Contribution from The Cornell Institute for Research in Chemical Ecology Baker Laboratory, Cornell University, Ithaca, NY 14853, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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