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rdf:type |
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lifeskim:mentions |
umls-concept:C0003069,
umls-concept:C0005149,
umls-concept:C0011155,
umls-concept:C0026809,
umls-concept:C0332206,
umls-concept:C0439097,
umls-concept:C1155013,
umls-concept:C1547348,
umls-concept:C1552644,
umls-concept:C1705241,
umls-concept:C1823153,
umls-concept:C2349976
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pubmed:issue |
1
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pubmed:dateCreated |
1992-3-25
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pubmed:abstractText |
The gamma delta T cell receptor (TCR) of the hybridoma KN6 recognizes the self molecule encoded by a class I gene which maps within the TL region of the major histocompatibility complex (MHC) of H-2b mice. Mice transgenic (Tg) for this TCR were crossed with mice genetically deficient in beta 2-microglobulin (beta 2m). No mature Tg gamma delta T cells were detected in the thymus or the spleen of the beta 2m- gamma delta Tg mice. We conclude that interaction between the Tg gamma delta TCR and a beta 2m-associated molecule (probably an MHC class I molecule) is required for the generation of mature Tg gamma delta T cells.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-1673361,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-1968084,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-1986381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2112266,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2117275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2139497,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2154700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2228044,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2236011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2308634,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2326267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2379238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2435787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2461518,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2476238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2493727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2526925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2528072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2528206,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2571940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2573841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2590942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2594068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2685607,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2784150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2784545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2785580,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2787028,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2788186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2788280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2847872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2883729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2885757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2885839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-2968521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3102971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3102972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3260917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3262831,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3263574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3289569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-3499575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-6606682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-6823332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1531458-6976410
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD24,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/Cd24a protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell...,
http://linkedlifedata.com/resource/pubmed/chemical/beta 2-Microglobulin
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0261-4189
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-31
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pubmed:dateRevised |
2010-9-7
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pubmed:meshHeading |
pubmed-meshheading:1531458-Animals,
pubmed-meshheading:1531458-Mice,
pubmed-meshheading:1531458-Spleen,
pubmed-meshheading:1531458-Thymus Gland,
pubmed-meshheading:1531458-Embryo, Mammalian,
pubmed-meshheading:1531458-Mice, Inbred Strains,
pubmed-meshheading:1531458-Base Sequence,
pubmed-meshheading:1531458-Cell Differentiation,
pubmed-meshheading:1531458-Genotype,
pubmed-meshheading:1531458-Crosses, Genetic,
pubmed-meshheading:1531458-Molecular Sequence Data,
pubmed-meshheading:1531458-Immunohistochemistry,
pubmed-meshheading:1531458-T-Lymphocytes
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