Linked Life Data

15312696

Source:http://linkedlifedata.com/resource/pubmed/id/15312696

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-8-17
pubmed:abstractText
This study examined the role of low density lipoprotein (LDL) cholesterol level in the association between Dopamine D4 receptor (DRD4) polymorphism and temperament dimension novelty seeking. From the on-going population based study of "Cardiovascular Risk in Young Finns", 78 men and women responded to the novelty seeking scale of the temperament and character inventory [Archives of General Psychiatry 44 (1987) 573] and were apolipoprotein E (apoE) and DRD4 genotyped. DRD4 polymorphism was related to disorderliness, a component of novelty seeking, in subjects with high LDL cholesterol level but not in subjects with low LDL cholesterol level. This finding did not change after adjustment for apoE polymorphism. Our findings suggest that the genetic determination of temperament may be dependent on biological factors, such as LDL cholesterol.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0301-0511
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
79-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Does the level of LDL cholesterol moderate a relationship between DRD4 and novelty seeking?
pubmed:affiliation
Department of Psychology, PO Box 9, University of Helsinki, FIN 00014 Helsinki, Finland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't