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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-8-13
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pubmed:abstractText |
Enzymatic breakdown of the extracellular matrix, and possibly local inflammation, contributes to intervertebral disc degeneration. We investigated whether polymorphisms within the IL-1 gene locus are associated with lumbar disc degeneration and whether the effect of occupational physical load on disc degeneration is modified by the polymorphisms.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1044-3983
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
626-33
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15308963-Adult,
pubmed-meshheading:15308963-Gene Frequency,
pubmed-meshheading:15308963-Genotype,
pubmed-meshheading:15308963-Humans,
pubmed-meshheading:15308963-Interleukin-1,
pubmed-meshheading:15308963-Intervertebral Disc,
pubmed-meshheading:15308963-Lumbar Vertebrae,
pubmed-meshheading:15308963-Magnetic Resonance Imaging,
pubmed-meshheading:15308963-Male,
pubmed-meshheading:15308963-Middle Aged,
pubmed-meshheading:15308963-Occupations,
pubmed-meshheading:15308963-Polymorphism, Genetic,
pubmed-meshheading:15308963-Polymorphism, Single Nucleotide,
pubmed-meshheading:15308963-Questionnaires,
pubmed-meshheading:15308963-Spinal Diseases
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pubmed:year |
2004
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pubmed:articleTitle |
Interleukin 1 polymorphisms and intervertebral disc degeneration.
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pubmed:affiliation |
Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki, Finland. Svetlana.Solovieva@ttl.fi
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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