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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-8-13
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pubmed:abstractText |
A Phase I/II protocol for treating cutaneuos melanomas with BNCT was designed in Argentina by the Comisión Nacional de Energía Atómica and the medical center Instituto Roffo. The first of a cohort of thirty planned patients was treated on October 9, 2003. This article depicts the protocol-based procedure and describes the first clinical case, treatment regime and planning, patient irradiation, retrospective dosimetric analysis and clinical outcome. Considering the low acute skin toxicity and the complete response in 21 of the 25 subcutaneous melanoma nodules treated, a second irradiation was performed in a different location of the extremity of the same patient. The corresponding clinical outcome is still under evaluation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0969-8043
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pubmed:author |
pubmed-author:ArgerichCC,
pubmed-author:BatistoniD ADA,
pubmed-author:BlaumannH RHR,
pubmed-author:BonomiM RMR,
pubmed-author:Calzetta LarrieuO AOA,
pubmed-author:CastigliaS GSG,
pubmed-author:DagrosaM AMA,
pubmed-author:FalkH CHC,
pubmed-author:GonzálezS JSJ,
pubmed-author:Jiménez RebagliatiRR,
pubmed-author:LibermanS JSJ,
pubmed-author:LonghiniLL,
pubmed-author:MenéndezPP,
pubmed-author:RothB M CBM,
pubmed-author:Santa CruzG AGA
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1101-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15308199-Argentina,
pubmed-meshheading:15308199-Boron,
pubmed-meshheading:15308199-Boron Compounds,
pubmed-meshheading:15308199-Boron Neutron Capture Therapy,
pubmed-meshheading:15308199-Clinical Protocols,
pubmed-meshheading:15308199-Female,
pubmed-meshheading:15308199-Fructose,
pubmed-meshheading:15308199-Humans,
pubmed-meshheading:15308199-Melanoma,
pubmed-meshheading:15308199-Middle Aged,
pubmed-meshheading:15308199-Radiotherapy Planning, Computer-Assisted,
pubmed-meshheading:15308199-Skin Neoplasms,
pubmed-meshheading:15308199-Treatment Outcome
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pubmed:year |
2004
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pubmed:articleTitle |
First BNCT treatment of a skin melanoma in Argentina: dosimetric analysis and clinical outcome.
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pubmed:affiliation |
Comisión Nacional de Energía Atómica, Av. Del Libertador 8250, (1429) Ciudad de Buenos Aires, Argentina. srgonzal@cnea.gov.ar
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, Non-P.H.S.,
Case Reports,
Clinical Trial, Phase II,
Clinical Trial, Phase I
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