Source:http://linkedlifedata.com/resource/pubmed/id/15307912
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2004-8-13
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pubmed:abstractText |
Liver toxicity is a common side effect of antiretroviral therapy, particularly in subjects coinfected with the hepatitis C virus (HCV). The incidence of severe liver toxicity after initiation of treatment with lopinavir (LPV) as well as its possible association with LPV plasma levels were assessed in 120 HIV-infected patients (52% coinfected by HCV). The incidence of severe liver toxicity at 3 months was 1.7% and the cumulative incidence at 12 months was 4%. The development of severe liver toxicity was associated with HCV coinfection but not with LPV plasma levels.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0889-2229
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
698-700
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15307912-Adult,
pubmed-meshheading:15307912-Anti-HIV Agents,
pubmed-meshheading:15307912-CD4 Lymphocyte Count,
pubmed-meshheading:15307912-Female,
pubmed-meshheading:15307912-HIV Infections,
pubmed-meshheading:15307912-Hepatitis C,
pubmed-meshheading:15307912-Humans,
pubmed-meshheading:15307912-Incidence,
pubmed-meshheading:15307912-Liver,
pubmed-meshheading:15307912-Lopinavir,
pubmed-meshheading:15307912-Male,
pubmed-meshheading:15307912-Pyrimidinones
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pubmed:year |
2004
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pubmed:articleTitle |
Short communication: liver toxicity of lopinavir-containing regimens in HIV-infected patients with or without hepatitis C coinfection.
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pubmed:affiliation |
Service of Infectious Diseases and Pharmacy Unit, Hospital Carlos III, 28035 Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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