Source:http://linkedlifedata.com/resource/pubmed/id/15305940
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2004-8-12
|
| pubmed:abstractText |
The role of pet keeping during infancy for the development of allergy and asthma is still controversial. The objective of this population-based birth cohort study was to assess the development of atopy and different wheezing phenotypes during the first 4 yr of life in relation to heredity and early pet keeping. The cohort comprised all 1228 infants living in a Swedish county who were born over a 1-yr period. The parents replied to repeated questionnaires and 817 of the children were skin prick tested both at 1 and 4 yr. Cat keeping during the first year of life was associated with an increased risk of a positive skin prick test to cat at 1 yr of age [odds ratio (OR) 2.2, 95% confidence interval (CI) 0.9-5.6], but neither with sensitivity nor clinical symptoms of allergy at 4 yr. Dog keeping during the first year of life was associated with an increased risk of early-onset transient wheezing, but only in children with parental asthma (adjusted OR 4.3, 95% CI 1.5-12.1). In contrast, early dog keeping had an inverse association with sensitivity to pollen allergen at 4 yr (adjusted OR 0.3, 95% CI 0.1-0.9) and late-onset wheezing (adjusted OR 0.4, 95% CI 0.2-1.0). Thus, pet keeping during the first year of life was not associated with an increased risk of atopy at 4 yr, although a positive SPT to cat was more common at 1 yr. Our findings may even suggest that dog keeping during the first year of life might provide some protection from pollen allergy and late-onset wheezing and increase the risk of early-onset transient wheezing in children with heredity for asthma.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0905-6157
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
316-22
|
| pubmed:dateRevised |
2008-5-28
|
| pubmed:meshHeading |
pubmed-meshheading:15305940-Animals,
pubmed-meshheading:15305940-Asthma,
pubmed-meshheading:15305940-Cats,
pubmed-meshheading:15305940-Child, Preschool,
pubmed-meshheading:15305940-Cohort Studies,
pubmed-meshheading:15305940-Dogs,
pubmed-meshheading:15305940-Environmental Illness,
pubmed-meshheading:15305940-Female,
pubmed-meshheading:15305940-Humans,
pubmed-meshheading:15305940-Hypersensitivity,
pubmed-meshheading:15305940-Infant,
pubmed-meshheading:15305940-Infant, Newborn,
pubmed-meshheading:15305940-Pregnancy,
pubmed-meshheading:15305940-Prevalence,
pubmed-meshheading:15305940-Questionnaires,
pubmed-meshheading:15305940-Respiratory Sounds,
pubmed-meshheading:15305940-Skin Tests,
pubmed-meshheading:15305940-Sweden
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
Development of atopy and wheezing symptoms in relation to heredity and early pet keeping in a Swedish birth cohort.
|
| pubmed:affiliation |
Department of Paediatrics, Ostersund Hospital, Ostersund, Sweden. annasandin@telia.com
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|