Source:http://linkedlifedata.com/resource/pubmed/id/15304988
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
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| pubmed:dateCreated |
2004-8-12
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| pubmed:abstractText |
Deuterium incorporation at the C-3 position of flavanones was achieved by treatment of flavanones and 2'-hydroxychalcones with D3PO4 and AcOD. We propose that the deuteration reaction mechanism for 2'-hydroxychalcones substrates is as follows. In the first step, 2'-hydroxychalcones cyclize to the corresponding flavanones by an intramolecular Michael-type reaction. Then deuteriums are incorporated into the flavanones via enolization.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
0009-2363
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
52
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
953-6
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| pubmed:meshHeading | |
| pubmed:year |
2004
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| pubmed:articleTitle |
Synthesis of deuterium-labeled flavanones.
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| pubmed:affiliation |
Department of Organic Synthesis, School of Pharmaceutical Sciences, Kitasato UniversityTokyo 108-8641, Japan. kagawah@pharm.kitasato-u.ac.jp
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| pubmed:publicationType |
Journal Article
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