|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2004-8-12
|
|
pubmed:abstractText |
We have previously reported that recombinant gamma 275Cys fibrinogen exhibits a marked impairment of functions as well as aberrant fibrin clot and bundle structures, as compared with wild-type, gamma 275Arg, and plasma fibrinogen from a heterozygous proband. Since gamma Arg275His mutations have also been reported in 10 families, we synthesized recombinant gamma 275His fibrinogen and gamma 275Ala fibrinogen (as a control) and analyzed and compared them with gamma 275Cys and gamma 275Arg.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1538-7933
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
2
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1359-67
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15304042-Alanine,
pubmed-meshheading:15304042-Animals,
pubmed-meshheading:15304042-CHO Cells,
pubmed-meshheading:15304042-Catalysis,
pubmed-meshheading:15304042-Cricetinae,
pubmed-meshheading:15304042-Cross-Linking Reagents,
pubmed-meshheading:15304042-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:15304042-Factor XIIIa,
pubmed-meshheading:15304042-Fibrin,
pubmed-meshheading:15304042-Fibrinogen,
pubmed-meshheading:15304042-Histidine,
pubmed-meshheading:15304042-Humans,
pubmed-meshheading:15304042-Microscopy, Electron, Scanning,
pubmed-meshheading:15304042-Plasmids,
pubmed-meshheading:15304042-Polymers,
pubmed-meshheading:15304042-Recombinant Proteins,
pubmed-meshheading:15304042-Spectrophotometry,
pubmed-meshheading:15304042-Thrombin,
pubmed-meshheading:15304042-Time Factors,
pubmed-meshheading:15304042-Ultraviolet Rays
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Comparison of thrombin-catalyzed fibrin polymerization and factor XIIIa-catalyzed cross-linking of fibrin among three recombinant variant fibrinogens, gamma 275C, gamma 275H, and gamma 275A.
|
|
pubmed:affiliation |
Department of Pathology, Shinshu University School of Medicine, Shinshu University Hospital, Japan.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
