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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10 Suppl
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pubmed:dateCreated |
1992-10-20
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pubmed:abstractText |
Seven days after a subcutaneous inoculation of 5 x 10(5) P388 leukemia cells into the foot pad of the left hind paw of donor mouse, aclarubicin (0.2mg/kg body weight) was injected subcutaneously into the hind paw of the opposite foot pad in the form of ACR-CH or aclarubicin aqueous solution. On day 10, the left popliteal and the lower para-aortic lymph nodes taken from each donor were transferred intraperitoneally to a normal recipient mouse. The combined survival time of recipients and the viable P388 leukemia cell number in popliteal and para-aortic lymph nodes were estimated with a calibration formula. Our results showed that the survival curve of recipients given ACR-CH was statistically improved compared with that of other treatment groups.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1560-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1530308-Aclarubicin,
pubmed-meshheading:1530308-Animals,
pubmed-meshheading:1530308-Carbon,
pubmed-meshheading:1530308-Drug Delivery Systems,
pubmed-meshheading:1530308-Leukemia P388,
pubmed-meshheading:1530308-Lymphatic Metastasis,
pubmed-meshheading:1530308-Mice,
pubmed-meshheading:1530308-Povidone
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pubmed:year |
1992
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pubmed:articleTitle |
[Enhancement of therapeutic efficacy of aclarubicin against lymph node metastases using a new dosage form: aclarubicin adsorbed on activated carbon particles].
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pubmed:affiliation |
First Dept. of Surgery, Kyoto Prefectural University of Medicine.
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pubmed:publicationType |
Journal Article,
English Abstract
|