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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2004-8-9
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pubmed:abstractText |
Individuals with nonmelanoma skin cancer (NMSC) are at increased risk of developing subsequent cancers. Genetic predisposition to reduced DNA repair capacity may be an underlying susceptibility factor explaining the excess risk of malignancies. To test this hypothesis, a cohort study was conducted to examine the association between XPD Lys751Gln polymorphism and risk of a second primary cancer in individuals with NMSC.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1055-9965
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1271-5
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15298945-Age Distribution,
pubmed-meshheading:15298945-Aged,
pubmed-meshheading:15298945-Alleles,
pubmed-meshheading:15298945-Carcinoma, Basal Cell,
pubmed-meshheading:15298945-Carcinoma, Squamous Cell,
pubmed-meshheading:15298945-Cohort Studies,
pubmed-meshheading:15298945-Confidence Intervals,
pubmed-meshheading:15298945-DNA Helicases,
pubmed-meshheading:15298945-DNA-Binding Proteins,
pubmed-meshheading:15298945-Female,
pubmed-meshheading:15298945-Genetic Predisposition to Disease,
pubmed-meshheading:15298945-Genotype,
pubmed-meshheading:15298945-Humans,
pubmed-meshheading:15298945-Male,
pubmed-meshheading:15298945-Middle Aged,
pubmed-meshheading:15298945-Neoplasms, Second Primary,
pubmed-meshheading:15298945-Polymorphism, Genetic,
pubmed-meshheading:15298945-Prevalence,
pubmed-meshheading:15298945-Prognosis,
pubmed-meshheading:15298945-Proportional Hazards Models,
pubmed-meshheading:15298945-Risk Assessment,
pubmed-meshheading:15298945-Sex Distribution,
pubmed-meshheading:15298945-Skin Neoplasms,
pubmed-meshheading:15298945-Survival Rate,
pubmed-meshheading:15298945-Transcription Factors,
pubmed-meshheading:15298945-Xeroderma Pigmentosum Group D Protein
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pubmed:year |
2004
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pubmed:articleTitle |
XPD polymorphism and risk of subsequent cancer in individuals with nonmelanoma skin cancer.
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pubmed:affiliation |
Department of Clinical Cancer Prevention, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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