rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2004-8-6
|
pubmed:abstractText |
Cohort and case-control genetic association studies offer the greatest power to detect small genotypic influences on disease phenotypes, relative to family-based designs. However, genetic subdivisions could confound studies involving unrelated individuals, but the topic has been little investigated. We examined geographical and interallelic association of SNP and microsatellite haplotypes of the Y chromosome, of regions of chromosome 11, and of autosomal SNP genotypes relevant to cardiovascular risk traits in a UK-wide epidemiological survey.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-5652
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
57
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
142-55
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15297808-Alleles,
pubmed-meshheading:15297808-Base Sequence,
pubmed-meshheading:15297808-Cardiovascular Diseases,
pubmed-meshheading:15297808-Case-Control Studies,
pubmed-meshheading:15297808-Chromosomes, Human, Y,
pubmed-meshheading:15297808-Cohort Studies,
pubmed-meshheading:15297808-European Continental Ancestry Group,
pubmed-meshheading:15297808-Genetic Testing,
pubmed-meshheading:15297808-Genetics, Population,
pubmed-meshheading:15297808-Genotype,
pubmed-meshheading:15297808-Geography,
pubmed-meshheading:15297808-Great Britain,
pubmed-meshheading:15297808-Haplotypes,
pubmed-meshheading:15297808-Humans,
pubmed-meshheading:15297808-Male,
pubmed-meshheading:15297808-Microsatellite Repeats,
pubmed-meshheading:15297808-Middle Aged,
pubmed-meshheading:15297808-Molecular Sequence Data,
pubmed-meshheading:15297808-Polymerase Chain Reaction,
pubmed-meshheading:15297808-Polymorphism, Single Nucleotide,
pubmed-meshheading:15297808-Research Design,
pubmed-meshheading:15297808-Sequence Analysis, DNA
|
pubmed:year |
2004
|
pubmed:articleTitle |
Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: implications for association analyses.
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pubmed:affiliation |
Human Genetics Division, School of Medicine, University of Southampton, Southampton General Hospital, England.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|