| pubmed-article:15297631 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C2936350 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C1510411 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C0018270 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C2003913 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:15297631 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:15297631 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:15297631 | pubmed:dateCreated | 2004-9-24 | lld:pubmed |
| pubmed-article:15297631 | pubmed:abstractText | Transforming growth factor-beta (TGF-beta) is a growth factor/cytokine involved in vascular remodeling and atherogenesis. Recent studies in apolipoprotein E-deficient mice have demonstrated a pivotal role of TGF-beta in the maintenance of the balance between inflammation and fibrosis in atherosclerotic plaques. Furthermore, inhibition of TGF-beta signaling has been shown to accelerate plaque formation and its progression toward an unstable phenotype in mice. However, if this mechanism is operative also in humans is still unknown. The aim of this study was to characterize the expression of TGF-beta1 in human carotid plaque and to correlate it with the extent of inflammatory infiltration and collagen content with the clinical signs of plaque instability. | lld:pubmed |
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| pubmed-article:15297631 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:15297631 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15297631 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15297631 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:15297631 | pubmed:issn | 1524-4628 | lld:pubmed |
| pubmed-article:15297631 | pubmed:author | pubmed-author:PorrecaEttore... | lld:pubmed |
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| pubmed-article:15297631 | pubmed:author | pubmed-author:CuccurulloChi... | lld:pubmed |
| pubmed-article:15297631 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:15297631 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:15297631 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15297631 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15297631 | pubmed:pagination | 2253-7 | lld:pubmed |
| pubmed-article:15297631 | pubmed:dateRevised | 2007-4-24 | lld:pubmed |
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| pubmed-article:15297631 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15297631 | pubmed:articleTitle | Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques. | lld:pubmed |
| pubmed-article:15297631 | pubmed:affiliation | Department of Medicine and Aging, School of Medicine, and Aging Research Center, Ce.S.I. Gabriele d'Annunzio University Foundation, Chieti-Pescara, Italy. fcipollone@unich.it | lld:pubmed |
| pubmed-article:15297631 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15297631 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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