|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
15
|
|
pubmed:dateCreated |
2004-8-6
|
|
pubmed:abstractText |
Histologically positive bronchial margins after resection for non-small cell lung cancer are associated with shortened patient survival due to local recurrence. We hypothesized that DNA promoter hypermethylation changes at bronchial margins could be detected in patients with no histological evidence of malignancy and that they would reflect epigenetic events in the primary tumor.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
5131-6
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:15297416-Adult,
pubmed-meshheading:15297416-Aged,
pubmed-meshheading:15297416-Aged, 80 and over,
pubmed-meshheading:15297416-Bronchi,
pubmed-meshheading:15297416-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:15297416-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:15297416-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:15297416-DNA,
pubmed-meshheading:15297416-DNA Methylation,
pubmed-meshheading:15297416-Female,
pubmed-meshheading:15297416-Humans,
pubmed-meshheading:15297416-Lung Neoplasms,
pubmed-meshheading:15297416-Male,
pubmed-meshheading:15297416-Middle Aged,
pubmed-meshheading:15297416-Neoplasm Metastasis,
pubmed-meshheading:15297416-Polymerase Chain Reaction,
pubmed-meshheading:15297416-Promoter Regions, Genetic,
pubmed-meshheading:15297416-Recurrence,
pubmed-meshheading:15297416-Time Factors,
pubmed-meshheading:15297416-Treatment Outcome
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Promoter hypermethylation of resected bronchial margins: a field defect of changes?
|
|
pubmed:affiliation |
Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
