| pubmed-article:15291404 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C0023779 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C0015689 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C0762662 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C1327413 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C1523116 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C1515999 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C1550147 | lld:lifeskim |
| pubmed-article:15291404 | lifeskim:mentions | umls-concept:C1709305 | lld:lifeskim |
| pubmed-article:15291404 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15291404 | pubmed:dateCreated | 2004-8-4 | lld:pubmed |
| pubmed-article:15291404 | pubmed:abstractText | Omega-3 lipid pretreatment significantly decreases TNF-alpha production in LPS-stimulated Mphis; however, this response is only a partial inhibition, suggesting that other nonsubstrate- (lipid) dependent mechanisms are involved. The cyclooxygenase (COX)-2 enzyme is principally responsible for lipid metabolism; thus, a selective COX-2 inhibitor (Rofecoxib) would clarify if it is an omega-3 lipid direct effect or a COX-2 enzyme-associated modulated reduction in TNF-alpha. Moreover, potential synergy between omega-3 lipids and selective COX-2 inhibition is postulated. | lld:pubmed |
| pubmed-article:15291404 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15291404 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15291404 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15291404 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15291404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15291404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15291404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15291404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15291404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15291404 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15291404 | pubmed:issn | 0148-6071 | lld:pubmed |
| pubmed-article:15291404 | pubmed:author | pubmed-author:ZhaoYou-YangY... | lld:pubmed |
| pubmed-article:15291404 | pubmed:author | pubmed-author:HeltonW... | lld:pubmed |
| pubmed-article:15291404 | pubmed:author | pubmed-author:EspatN... | lld:pubmed |
| pubmed-article:15291404 | pubmed:author | pubmed-author:AnwarKhandake... | lld:pubmed |
| pubmed-article:15291404 | pubmed:author | pubmed-author:BabcockTricia... | lld:pubmed |
| pubmed-article:15291404 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15291404 | pubmed:volume | 28 | lld:pubmed |
| pubmed-article:15291404 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15291404 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15291404 | pubmed:pagination | 232-9; discussion 239-40 | lld:pubmed |
| pubmed-article:15291404 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:15291404 | pubmed:articleTitle | Synergistic anti-inflammatory activity of omega-3 lipid and rofecoxib pretreatment on macrophage proinflammatory cytokine production occurs via divergent NF-kappaB activation. | lld:pubmed |
| pubmed-article:15291404 | pubmed:affiliation | Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA. | lld:pubmed |
| pubmed-article:15291404 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15291404 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
