|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0015295,
umls-concept:C0017337,
umls-concept:C0017428,
umls-concept:C0022009,
umls-concept:C0204727,
umls-concept:C0205409,
umls-concept:C0336791,
umls-concept:C0752046,
umls-concept:C1415498,
umls-concept:C1426072,
umls-concept:C1519249,
umls-concept:C1704675
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2004-8-3
|
|
pubmed:abstractText |
Genome Analyzer (GenoA) with a relational database back-end, was developed to extract information from mammalian genomic sequences. This data mining and visualization tool-set enables laboratory bench scientists to identify and assemble virtual cDNA from genomic exon sequences, and provides a starting point to identify potential alternative splice variants and polymorphisms in silico. The study described in this paper demonstrates the use of GenoA to study human brain hyperpolarization-activated cation channel genes HCN1 and HCN3.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0219-7200
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
1
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
433-46
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15290763-Amino Acid Sequence,
pubmed-meshheading:15290763-Animals,
pubmed-meshheading:15290763-Base Sequence,
pubmed-meshheading:15290763-Computational Biology,
pubmed-meshheading:15290763-Cyclic Nucleotide-Gated Cation Channels,
pubmed-meshheading:15290763-DNA,
pubmed-meshheading:15290763-Databases, Genetic,
pubmed-meshheading:15290763-Exons,
pubmed-meshheading:15290763-Genomics,
pubmed-meshheading:15290763-Humans,
pubmed-meshheading:15290763-Ion Channels,
pubmed-meshheading:15290763-Mice,
pubmed-meshheading:15290763-Molecular Sequence Data,
pubmed-meshheading:15290763-Nerve Tissue Proteins,
pubmed-meshheading:15290763-Polymorphism, Single Nucleotide,
pubmed-meshheading:15290763-Potassium Channels,
pubmed-meshheading:15290763-Rats,
pubmed-meshheading:15290763-Sequence Alignment,
pubmed-meshheading:15290763-Software Design
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
An interactive tool for extracting exons and SNP from genomic sequence: isolation of HCN1 and HCN3 ion channel genes.
|
|
pubmed:affiliation |
Department of Bioinformatics, Merck & Co., Inc., WP53F-3001, West Point, PA 19486, USA. yuan_liu@merck.com
|
|
pubmed:publicationType |
Journal Article
|
