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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-8-3
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pubmed:abstractText |
Our objective was to investigate the effect of the CYP3A5 genotype on the systemic clearance of midazolam in constitutive, inhibited, and induced metabolic conditions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/Itraconazole,
http://linkedlifedata.com/resource/pubmed/chemical/Midazolam,
http://linkedlifedata.com/resource/pubmed/chemical/Rifampin
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0009-9236
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pubmed:author |
pubmed-author:ChoJoo-YounJY,
pubmed-author:ChungJae-YongJY,
pubmed-author:HongKyoung-SeopKS,
pubmed-author:JangIn-JinIJ,
pubmed-author:KimJung-RyulJR,
pubmed-author:LimHyeong-SeokHS,
pubmed-author:LiuKwang-HyeonKH,
pubmed-author:OhDal-SeokDS,
pubmed-author:ShinJae-GookJG,
pubmed-author:ShinSang-GooSG,
pubmed-author:YiSo-YoungSY,
pubmed-author:YuKyung-SangKS
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pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-12
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15289787-Adult,
pubmed-meshheading:15289787-Asian Continental Ancestry Group,
pubmed-meshheading:15289787-Biological Availability,
pubmed-meshheading:15289787-Biotransformation,
pubmed-meshheading:15289787-Cytochrome P-450 CYP3A,
pubmed-meshheading:15289787-Cytochrome P-450 Enzyme System,
pubmed-meshheading:15289787-Female,
pubmed-meshheading:15289787-Genetic Variation,
pubmed-meshheading:15289787-Genotype,
pubmed-meshheading:15289787-Humans,
pubmed-meshheading:15289787-Infusions, Intravenous,
pubmed-meshheading:15289787-Itraconazole,
pubmed-meshheading:15289787-Male,
pubmed-meshheading:15289787-Metabolic Clearance Rate,
pubmed-meshheading:15289787-Midazolam,
pubmed-meshheading:15289787-Pharmacogenetics,
pubmed-meshheading:15289787-Polymorphism, Genetic,
pubmed-meshheading:15289787-Prospective Studies,
pubmed-meshheading:15289787-Rifampin,
pubmed-meshheading:15289787-Sensitivity and Specificity
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pubmed:year |
2004
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pubmed:articleTitle |
Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states.
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pubmed:affiliation |
Department of Pharmacology and Clinical Pharmacology Unit, Seoul National University College of Medicine and Hospital, Seoul, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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