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rdf:type |
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lifeskim:mentions |
umls-concept:C0003483,
umls-concept:C0009813,
umls-concept:C0014239,
umls-concept:C0018787,
umls-concept:C0038435,
umls-concept:C0162638,
umls-concept:C0225828,
umls-concept:C0333959,
umls-concept:C0439590,
umls-concept:C1261287,
umls-concept:C1760025,
umls-concept:C1880177,
umls-concept:C2684089
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pubmed:issue |
6
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pubmed:dateCreated |
2004-8-10
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pubmed:abstractText |
The endoplasmic reticulum (ER) is recognized as an organelle that participates in folding secretory and membrane proteins. The ER responds to stress by upregulating ER chaperones, but prolonged and/or excess ER stress leads to apoptosis. However, the potential role of ER stress in pathophysiological hearts remains unclear.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II Type 1 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Molecular Chaperones,
http://linkedlifedata.com/resource/pubmed/chemical/Natriuretic Peptide, Brain,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Thapsigargin,
http://linkedlifedata.com/resource/pubmed/chemical/Tunicamycin,
http://linkedlifedata.com/resource/pubmed/chemical/olmesartan,
http://linkedlifedata.com/resource/pubmed/chemical/olmesartan medoxomil
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:FujitaMasashiM,
pubmed-author:HirataAkioA,
pubmed-author:HoriMasatsuguM,
pubmed-author:KitakazeMasafumiM,
pubmed-author:LiaoYulinY,
pubmed-author:MinaminoTetsuoT,
pubmed-author:NagamachiYokoY,
pubmed-author:NakataniTakeshiT,
pubmed-author:OgawaSatoshiS,
pubmed-author:OkadaKen-ichiroK,
pubmed-author:OzawaKentaroK,
pubmed-author:TakashimaSeijiS,
pubmed-author:TomoikeHitonobuH,
pubmed-author:TsukamotoOsamuO,
pubmed-author:TsukamotoYoshitaneY,
pubmed-author:YutaniChikaoC
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
705-12
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15289376-Angiotensin II,
pubmed-meshheading:15289376-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:15289376-Animals,
pubmed-meshheading:15289376-Aortic Valve Stenosis,
pubmed-meshheading:15289376-Apoptosis,
pubmed-meshheading:15289376-Cardiomegaly,
pubmed-meshheading:15289376-Cells, Cultured,
pubmed-meshheading:15289376-Disease Models, Animal,
pubmed-meshheading:15289376-Disease Progression,
pubmed-meshheading:15289376-Endoplasmic Reticulum,
pubmed-meshheading:15289376-Gene Expression Regulation,
pubmed-meshheading:15289376-Heart Failure,
pubmed-meshheading:15289376-Humans,
pubmed-meshheading:15289376-Imidazoles,
pubmed-meshheading:15289376-Ligation,
pubmed-meshheading:15289376-Male,
pubmed-meshheading:15289376-Mice,
pubmed-meshheading:15289376-Mice, Inbred C57BL,
pubmed-meshheading:15289376-Molecular Chaperones,
pubmed-meshheading:15289376-Myocytes, Cardiac,
pubmed-meshheading:15289376-Natriuretic Peptide, Brain,
pubmed-meshheading:15289376-RNA, Messenger,
pubmed-meshheading:15289376-Rats,
pubmed-meshheading:15289376-Rats, Inbred WKY,
pubmed-meshheading:15289376-Signal Transduction,
pubmed-meshheading:15289376-Stress, Physiological,
pubmed-meshheading:15289376-Tetrazoles,
pubmed-meshheading:15289376-Thapsigargin,
pubmed-meshheading:15289376-Tunicamycin
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pubmed:year |
2004
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pubmed:articleTitle |
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis.
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pubmed:affiliation |
Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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