Linked Life Data

15288252

Source:http://linkedlifedata.com/resource/pubmed/id/15288252

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-8-3
pubmed:abstractText
The recent human genome initiatives have led to the discovery of a multitude of genes that are potentially associated with various pathologic conditions and, thus, have opened new horizons in drug discovery. Simultaneously, annotated chemical libraries have emerged as information-rich databases to integrate biological and chemical data. They can be useful for the discovery of new pharmaceutical leads, the validation of new biotargets and the determination of the structural basis of ligand selectivity within target families. Annotated libraries provide a strong information basis for computational design of target-directed combinatorial libraries, which are a key component of modern drug discovery. Today, the rational design of chemical libraries enhanced with chemogenomics data is a new area of progressive research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1367-5931
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
412-7
pubmed:dateRevised
2009-8-25
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Exploring the chemogenomic knowledge space with annotated chemical libraries.
pubmed:affiliation
Chemical Diversity Labs, Inc., 11558 Sorrento Valley Road, San Diego, California 92121, USA. ns@chemdiv.com
pubmed:publicationType
Journal Article, Review