Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-10-22
pubmed:abstractText
Salivary status and caries incidence were studied in 28 young, Type 1 diabetics from the onset of the disease and during a two-year period. Flow rate, buffer capacity, glucose content, total protein concentration and levels of mutans streptococci and lactobacilli were determined in stimulated whole saliva every third month. Dental caries was recorded at onset and then once a year. Forty-six per cent of the children developed caries during the observation period. Caries incidence was significantly higher (P less than 0.05) during the first year of diabetes, compared with the second. Caries-active children displayed significantly higher HbA1c levels (P less than 0.001), compared with caries-inactive diabetics. The number of salivary lactobacilli dropped significantly (P less than 0.05) during the first six months of the disease, while mutans streptococci levels remained unchanged during the study period. Salivary glucose concentration showed a considerable individual variation, but tended to be lower during the second year. The results suggest a possible relationship between Type 1 diabetes treatment and caries.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0164-1263
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
184-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:1528788-Adolescent, pubmed-meshheading:1528788-Analysis of Variance, pubmed-meshheading:1528788-Child, pubmed-meshheading:1528788-Child, Preschool, pubmed-meshheading:1528788-Colony Count, Microbial, pubmed-meshheading:1528788-DMF Index, pubmed-meshheading:1528788-Dental Caries, pubmed-meshheading:1528788-Dental Caries Susceptibility, pubmed-meshheading:1528788-Diabetes Mellitus, Type 1, pubmed-meshheading:1528788-Female, pubmed-meshheading:1528788-Glucose, pubmed-meshheading:1528788-Humans, pubmed-meshheading:1528788-Incidence, pubmed-meshheading:1528788-Lactobacillus, pubmed-meshheading:1528788-Male, pubmed-meshheading:1528788-Saliva, pubmed-meshheading:1528788-Salivary Proteins and Peptides, pubmed-meshheading:1528788-Secretory Rate, pubmed-meshheading:1528788-Streptococcus mutans
pubmed:articleTitle
Two-year longitudinal observations of salivary status and dental caries in children with insulin-dependent diabetes mellitus.
pubmed:affiliation
Karolinska Institute, Stockholm.
pubmed:publicationType
Journal Article