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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-8-2
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pubmed:abstractText |
Designer T cells are T lymphocytes engineered toward specific antibody-type membrane antigens through chimeric immunoglobulin-T-cell receptor (IgTCR) genes that have been used for adoptive cellular immunotherapy. We have extended this approach to prostate specific membrane antigen (PSMA) as a means to attack prostate cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamate Carboxypeptidase II,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Heavy Chains,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Light Chains,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/glutamate carboxypeptidase II, human
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12-25
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15287090-Animals,
pubmed-meshheading:15287090-Antibodies, Monoclonal,
pubmed-meshheading:15287090-Antigens, Surface,
pubmed-meshheading:15287090-Cell Line, Tumor,
pubmed-meshheading:15287090-Cloning, Molecular,
pubmed-meshheading:15287090-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:15287090-Flow Cytometry,
pubmed-meshheading:15287090-Glutamate Carboxypeptidase II,
pubmed-meshheading:15287090-Humans,
pubmed-meshheading:15287090-Immunoglobulin Heavy Chains,
pubmed-meshheading:15287090-Immunoglobulin Light Chains,
pubmed-meshheading:15287090-Immunotherapy, Adoptive,
pubmed-meshheading:15287090-Lymphocyte Activation,
pubmed-meshheading:15287090-Male,
pubmed-meshheading:15287090-Mice,
pubmed-meshheading:15287090-Mice, Inbred BALB C,
pubmed-meshheading:15287090-Mice, Nude,
pubmed-meshheading:15287090-Precipitin Tests,
pubmed-meshheading:15287090-Prostatic Neoplasms,
pubmed-meshheading:15287090-Receptors, Antigen, T-Cell,
pubmed-meshheading:15287090-Recombinant Fusion Proteins,
pubmed-meshheading:15287090-T-Lymphocytes
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pubmed:year |
2004
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pubmed:articleTitle |
Anti-prostate specific membrane antigen designer T cells for prostate cancer therapy.
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pubmed:affiliation |
Biotherapeutics Development Lab, Division of Hematology-Oncology, Beth Israel Deaconess Medical Center and Harvard Institute of Human Genetics, Harvard Medical School, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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