|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2004-7-29
|
|
pubmed:abstractText |
A significant proliferation of glial cells occurs in the spinal cord and brainstem of SOD1 G93A transgenic mice with familial amyotrophic lateral sclerosis (ALS). Since activated glia may contribute to motor neuron degeneration, we tested whether inhibition of gliosis using low-dose chemotherapy is beneficial in this mouse model.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0009-3157
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
50
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
138-42
|
|
pubmed:dateRevised |
2009-11-11
|
|
pubmed:meshHeading |
pubmed-meshheading:15282441-Age of Onset,
pubmed-meshheading:15282441-Amyotrophic Lateral Sclerosis,
pubmed-meshheading:15282441-Animals,
pubmed-meshheading:15282441-Antineoplastic Agents,
pubmed-meshheading:15282441-Astrocytes,
pubmed-meshheading:15282441-Cell Count,
pubmed-meshheading:15282441-Glial Fibrillary Acidic Protein,
pubmed-meshheading:15282441-Immunohistochemistry,
pubmed-meshheading:15282441-Mice,
pubmed-meshheading:15282441-Mice, Transgenic,
pubmed-meshheading:15282441-Microglia,
pubmed-meshheading:15282441-Plant Lectins,
pubmed-meshheading:15282441-Superoxide Dismutase,
pubmed-meshheading:15282441-Survival Rate,
pubmed-meshheading:15282441-Vincristine
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Chemotherapy delays progression of motor neuron disease in the SOD1 G93A transgenic mouse.
|
|
pubmed:affiliation |
Department of Anatomy and Cell Biology, Monash University, Melbourne, Australia.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
