Source:http://linkedlifedata.com/resource/pubmed/id/15282201
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
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| pubmed:dateCreated |
2004-10-26
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| pubmed:abstractText |
A cohort of 42,655 clients that were first registered with the Elderly Health Service in 2000 were followed prospectively through the tuberculosis (TB) notification registry until the end of 2002. A total of 286 active TB cases (186 culture confirmed) were identified. The annual TB notification rates were 735, 427, and 174 per 100,000 among current smokers, ex-smokers, and never-smokers, respectively (p < 0.001). The trend in TB risk persisted after the control of background characteristics using Cox proportional hazards analysis (adjusted hazard ratios [HRs]: 2.63, 1.41, and 1, p < 0.001). In comparison with never-smokers, current smokers had an excess risk of pulmonary TB (adjusted HR, 2.87; 95% confidence interval [CI], 2.00-4.11; p < 0.001), but not extrapulmonary TB (adjusted HR, 1.04; 95% CI, 0.33-3.30; p = 0.95). Among the current smokers, those who developed TB smoked more cigarettes per day than those who did not (13.43, SD 8.76 vs. 10.96, SD 7.87, p = 0.01). A statistically significant dose-response relationship was observed with respect to active TB and culture-confirmed TB (both p < 0.05). Smoking accounted for 32.8% (95% CI, 14.9-48.0%), 8.6% (95% CI, 3.3-15.1%), and 18.7% (95% CI, 7.7-30.4%) of the TB risk among males, females, and the entire cohort, respectively. Approximately 44.9% (95% CI, 20.7-64.6%) of the sex difference was attributable to smoking.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
1073-449X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
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| pubmed:volume |
170
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1027-33
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:15282201-Aged,
pubmed-meshheading:15282201-Aged, 80 and over,
pubmed-meshheading:15282201-Analysis of Variance,
pubmed-meshheading:15282201-Case-Control Studies,
pubmed-meshheading:15282201-Cohort Studies,
pubmed-meshheading:15282201-Comorbidity,
pubmed-meshheading:15282201-Confidence Intervals,
pubmed-meshheading:15282201-Female,
pubmed-meshheading:15282201-Geriatric Assessment,
pubmed-meshheading:15282201-Hong Kong,
pubmed-meshheading:15282201-Humans,
pubmed-meshheading:15282201-Incidence,
pubmed-meshheading:15282201-Male,
pubmed-meshheading:15282201-Probability,
pubmed-meshheading:15282201-Proportional Hazards Models,
pubmed-meshheading:15282201-Registries,
pubmed-meshheading:15282201-Severity of Illness Index,
pubmed-meshheading:15282201-Sex Distribution,
pubmed-meshheading:15282201-Smoking,
pubmed-meshheading:15282201-Survival Analysis,
pubmed-meshheading:15282201-Tuberculosis, Pulmonary
|
| pubmed:year |
2004
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| pubmed:articleTitle |
Smoking and tuberculosis among the elderly in Hong Kong.
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| pubmed:affiliation |
TB and Chest Service, Department of Community Medicine, The University of Hong Kong, China. cc_leung@dh.gov.hk
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|