Linked Life Data

15280452

Source:http://linkedlifedata.com/resource/pubmed/id/15280452

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:15280452rdf:typepubmed:Citationlld:pubmed
pubmed-article:15280452lifeskim:mentionsumls-concept:C0019704lld:lifeskim
pubmed-article:15280452lifeskim:mentionsumls-concept:C1516962lld:lifeskim
pubmed-article:15280452lifeskim:mentionsumls-concept:C0032659lld:lifeskim
pubmed-article:15280452lifeskim:mentionsumls-concept:C1556094lld:lifeskim
pubmed-article:15280452lifeskim:mentionsumls-concept:C1521797lld:lifeskim
pubmed-article:15280452lifeskim:mentionsumls-concept:C0205250lld:lifeskim
pubmed-article:15280452lifeskim:mentionsumls-concept:C0332183lld:lifeskim
pubmed-article:15280452pubmed:issue16lld:pubmed
pubmed-article:15280452pubmed:dateCreated2004-7-28lld:pubmed
pubmed-article:15280452pubmed:abstractTextAlthough Japan is classified as a country with a low prevalence of human immunodeficiency virus type 1 (HIV-1), domestic sexual transmission has been increasing steadily. Because 70% of the Japanese population expresses HLA-A24 (genotype HLA-A*2402), we wished to assess the effect of the dominant HLA type on the evolution and transmission of HIV-1 among the Japanese population. Twenty-three out of 25 A24-positive Japanese patients had a Y-to-F substitution at the second position [Nef138-10(2F)] in an immunodominant A24-restricted CTL epitope in their HIV-1 nef gene (Nef138-10). None of 12 A24-negative Japanese hemophiliacs but 9 out of 16 patients infected through unprotected sexual intercourse had Nef138-10(2F) (P < 0.01). Two of two A24-positive but none of six A24-negative Australians had Nef138-10(2F). Nef138-10(2F) peptides bound well to the HLA-A*2402 heavy chain; however, Nef138-10(2F) was expressed poorly on the cell surface from the native protein. Thus, HIV-1 with Nef138-10(2F) appears to be a cytotoxic-T-lymphocyte escape mutant and has been transmitted frequently by sexual contact among the highly A24-positive Japanese population.lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:languageenglld:pubmed
pubmed-article:15280452pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:citationSubsetIMlld:pubmed
pubmed-article:15280452pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:15280452pubmed:statusMEDLINElld:pubmed
pubmed-article:15280452pubmed:monthAuglld:pubmed
pubmed-article:15280452pubmed:issn0022-538Xlld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:NakamuraTetsu...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:KitamuraYoshi...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:IwamotoAikich...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:OdawaraTakash...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:CooperDavid...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:KelleherAntho...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:GotoMiekoMlld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:Kawana-Tachik...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:TomizawaMarik...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:HosoyaNoriaki...lld:pubmed
pubmed-article:15280452pubmed:authorpubmed-author:FurutsukiTaeTlld:pubmed
pubmed-article:15280452pubmed:issnTypePrintlld:pubmed
pubmed-article:15280452pubmed:volume78lld:pubmed
pubmed-article:15280452pubmed:ownerNLMlld:pubmed
pubmed-article:15280452pubmed:authorsCompleteYlld:pubmed
pubmed-article:15280452pubmed:pagination8437-45lld:pubmed
pubmed-article:15280452pubmed:dateRevised2011-11-17lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:meshHeadingpubmed-meshheading:15280452...lld:pubmed
pubmed-article:15280452pubmed:year2004lld:pubmed
pubmed-article:15280452pubmed:articleTitleFrequent transmission of cytotoxic-T-lymphocyte escape mutants of human immunodeficiency virus type 1 in the highly HLA-A24-positive Japanese population.lld:pubmed
pubmed-article:15280452pubmed:affiliationDivision of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.lld:pubmed
pubmed-article:15280452pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15280452pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:3105entrezgene:pubmedpubmed-article:15280452lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:15280452lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:15280452lld:pubmed
More...