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pubmed:abstractText |
Cystic Fibrosis is a pleiotropic disease in humans with primary morbidity and mortality associated with a lung disease phenotype. However, knockout in the mouse of cftr, the gene whose mutant alleles are responsible for cystic fibrosis, has previously failed to produce a readily, quantifiable lung phenotype.
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pubmed:affiliation |
Departments of Medicine and Physiology, Louisiana State University, School of Medicine, New Orleans, LA, 70112 USA. ccohen@lsuhsc.edu
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