Source:http://linkedlifedata.com/resource/pubmed/id/15279336
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
2004-7-28
|
pubmed:abstractText |
To determine the prevalence and clinical characteristics of lipodystrophy in HIV-infected Thai patients, a cross-sectional study was performed on 278 HIV-infected patients at Bamrasnaradura Infectious Disease Institute. Laboratory data related to lipid and glucose metabolism were obtained from both patients who self reported fat maldistribution or diagnosed by a physician. The history of antiretroviral treatment and HIV infection were recorded. Prevalence of lipodystrophy found in the present study was 17%. Lipodystrophy was reported mostly on the face, buttock, legs, arms, and abdomen respectively. Two-thirds of these patients had mixed syndromes of fat accumulation and fat wasting and the others had only fat wasting. Ninety-three percent of lipodystrophic patients had at least 1 abnormality in either lipid or glucose metabolism. Eighty-eight percent had dyslipidemia, 21% had impaired glucose tolerance, 30% had insulin resistance and 27% had diabetes mellitus. Lipodystrophic patients have a high rate of lipid and glucose metabolism abnormalities which are the major risk factors for cardiovascular events.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0125-2208
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
87
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
605-11
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15279336-Adult,
pubmed-meshheading:15279336-Cross-Sectional Studies,
pubmed-meshheading:15279336-Diabetes Mellitus,
pubmed-meshheading:15279336-Female,
pubmed-meshheading:15279336-HIV-Associated Lipodystrophy Syndrome,
pubmed-meshheading:15279336-Humans,
pubmed-meshheading:15279336-Insulin Resistance,
pubmed-meshheading:15279336-Male,
pubmed-meshheading:15279336-Middle Aged,
pubmed-meshheading:15279336-Prevalence,
pubmed-meshheading:15279336-Thailand
|
pubmed:year |
2004
|
pubmed:articleTitle |
Prevalence of lipodystrophy in Thai-HIV infected patients.
|
pubmed:affiliation |
Bamrasnaradura Infectious Disease Institute, Nonthaburi, Thailand.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|