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rdf:type |
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lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0017262,
umls-concept:C0036536,
umls-concept:C0036537,
umls-concept:C0078058,
umls-concept:C0123707,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0215848,
umls-concept:C0441655,
umls-concept:C1256770,
umls-concept:C1822686,
umls-concept:C2003941,
umls-concept:C2330894,
umls-concept:C2348110,
umls-concept:C2348977,
umls-concept:C2911684
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pubmed:issue |
8
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pubmed:dateCreated |
2004-7-27
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pubmed:abstractText |
To examine insulin-like growth factor (IGF)-1 stimulation of expression of hypoxia inducible factor (HIF)-1 alpha and secretion of vascular endothelial growth factor (VEGF) and IGF binding protein (IGFBP)-3 in human retinal pigment epithelial (RPE) cell line D407.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/HIF1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1, alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor Binding...,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Potassium-Exchanging ATPase,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/VEGFA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2838-47
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15277511-Cell Line,
pubmed-meshheading:15277511-Cell Polarity,
pubmed-meshheading:15277511-Humans,
pubmed-meshheading:15277511-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:15277511-Immunoblotting,
pubmed-meshheading:15277511-Insulin-Like Growth Factor Binding Protein 3,
pubmed-meshheading:15277511-Insulin-Like Growth Factor I,
pubmed-meshheading:15277511-Microscopy, Fluorescence,
pubmed-meshheading:15277511-Pigment Epithelium of Eye,
pubmed-meshheading:15277511-Sodium-Potassium-Exchanging ATPase,
pubmed-meshheading:15277511-Transcription Factors,
pubmed-meshheading:15277511-Up-Regulation,
pubmed-meshheading:15277511-Vascular Endothelial Growth Factor A
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pubmed:year |
2004
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pubmed:articleTitle |
IGF-1-induced VEGF and IGFBP-3 secretion correlates with increased HIF-1 alpha expression and activity in retinal pigment epithelial cell line D407.
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pubmed:affiliation |
Department of Cell and Molecular Pharmacology and Experimental Therapeutics and The Hollings Cancer Center, Medical University of South Carolina, Charleston, 29425, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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