Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-7-27
pubmed:abstractText
The clinical phenomenon of lung cancer metastasis to specific target organs is believed to be a direct interaction between tumor cells and extracellular matrix components. During invasion, tumor cells attach to the basement membrane protein, collagen type IV, degrade it, migrate through blood vessels, and adhere to extracellular matrix proteins.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1552-6259
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
450-7
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:15276495-Antigens, CD29, pubmed-meshheading:15276495-Carcinoma, Non-Small-Cell Lung, pubmed-meshheading:15276495-Cell Adhesion, pubmed-meshheading:15276495-Cell Division, pubmed-meshheading:15276495-Cell Line, Tumor, pubmed-meshheading:15276495-Cell Movement, pubmed-meshheading:15276495-Cell Size, pubmed-meshheading:15276495-Collagen Type IV, pubmed-meshheading:15276495-Culture Media, Serum-Free, pubmed-meshheading:15276495-Focal Adhesion Kinase 1, pubmed-meshheading:15276495-Focal Adhesion Protein-Tyrosine Kinases, pubmed-meshheading:15276495-Genistein, pubmed-meshheading:15276495-Humans, pubmed-meshheading:15276495-Lung Neoplasms, pubmed-meshheading:15276495-Microscopy, Video, pubmed-meshheading:15276495-Neoplasm Invasiveness, pubmed-meshheading:15276495-Neoplasm Proteins, pubmed-meshheading:15276495-Phosphorylation, pubmed-meshheading:15276495-Protein Processing, Post-Translational, pubmed-meshheading:15276495-Protein-Tyrosine Kinases, pubmed-meshheading:15276495-Pseudopodia, pubmed-meshheading:15276495-Vanadates
pubmed:year
2004
pubmed:articleTitle
Integrin-dependent protein tyrosine phosphorylation is a key regulatory event in collagen-IV-mediated adhesion and proliferation of human lung tumor cell line, Calu-1.
pubmed:affiliation
Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't