pubmed-article:1526872 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1526872 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
pubmed-article:1526872 | lifeskim:mentions | umls-concept:C0034603 | lld:lifeskim |
pubmed-article:1526872 | lifeskim:mentions | umls-concept:C0031082 | lld:lifeskim |
pubmed-article:1526872 | lifeskim:mentions | umls-concept:C0085101 | lld:lifeskim |
pubmed-article:1526872 | lifeskim:mentions | umls-concept:C0004400 | lld:lifeskim |
pubmed-article:1526872 | lifeskim:mentions | umls-concept:C0450363 | lld:lifeskim |
pubmed-article:1526872 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:1526872 | pubmed:dateCreated | 1992-10-22 | lld:pubmed |
pubmed-article:1526872 | pubmed:abstractText | Three-dimensional dose distributions have been calculated for LS174T human colon cancer xenografts in athymic nude mice treated with 131I-labeled 17-1A monoclonal antibody. Autoradiographs were made for fifteen to twenty 32-micron-thick representative serial sections of tumors removed 1 and 4 days postinjection. Film density readings were converted to activity density and entered into a radiotherapy treatment planning system. Three-dimensional dose distributions were obtained by summing the dose contributions due to each voxel of uniform activity. Isodoserate distributions and dose-rate-volume histograms for representative tumors at 1 and 4 days following 131I-labeled 17-1A injection showed a progressive change from a predominantly surface deposition (day 1) to a more volumetric deposition (day 4). Average tumor doses calculated using the assumptions of uniform source distribution and local dose deposition resulted in a poor estimation of the cumulative dose because of the significant time-dependent dose-rate nonuniformities. | lld:pubmed |
pubmed-article:1526872 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1526872 | pubmed:language | eng | lld:pubmed |
pubmed-article:1526872 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1526872 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1526872 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1526872 | pubmed:issn | 0360-3016 | lld:pubmed |
pubmed-article:1526872 | pubmed:author | pubmed-author:BuchsbaumD... | lld:pubmed |
pubmed-article:1526872 | pubmed:author | pubmed-author:Ten HakenR... | lld:pubmed |
pubmed-article:1526872 | pubmed:author | pubmed-author:RobersonP LPL | lld:pubmed |
pubmed-article:1526872 | pubmed:author | pubmed-author:HeidornD BDB | lld:pubmed |
pubmed-article:1526872 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1526872 | pubmed:volume | 24 | lld:pubmed |
pubmed-article:1526872 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1526872 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1526872 | pubmed:pagination | 329-34 | lld:pubmed |
pubmed-article:1526872 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:1526872 | pubmed:meshHeading | pubmed-meshheading:1526872-... | lld:pubmed |
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pubmed-article:1526872 | pubmed:meshHeading | pubmed-meshheading:1526872-... | lld:pubmed |
pubmed-article:1526872 | pubmed:meshHeading | pubmed-meshheading:1526872-... | lld:pubmed |
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pubmed-article:1526872 | pubmed:meshHeading | pubmed-meshheading:1526872-... | lld:pubmed |
pubmed-article:1526872 | pubmed:year | 1992 | lld:pubmed |
pubmed-article:1526872 | pubmed:articleTitle | Three-dimensional tumor dosimetry for radioimmunotherapy using serial autoradiography. | lld:pubmed |
pubmed-article:1526872 | pubmed:affiliation | Department of Radiation Oncology, University of Michigan, Ann Arbor. | lld:pubmed |
pubmed-article:1526872 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1526872 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |