pubmed-article:15267231 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15267231 | lifeskim:mentions | umls-concept:C1999216 | lld:lifeskim |
pubmed-article:15267231 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
pubmed-article:15267231 | lifeskim:mentions | umls-concept:C0379528 | lld:lifeskim |
pubmed-article:15267231 | pubmed:issue | 16 | lld:pubmed |
pubmed-article:15267231 | pubmed:dateCreated | 2004-7-22 | lld:pubmed |
pubmed-article:15267231 | pubmed:abstractText | Gamma-secretase is the second of two proteolytic enzymes responsible for the release of the amyloid beta-peptide implicated in the etiology of Alzheimer's disease. Here, we used solid-phase synthesis to generate a new series of helical peptides as gamma-secretase inhibitors, one of which, 11, showed an IC(50) of 140 pM in a cell-free enzyme assay. | lld:pubmed |
pubmed-article:15267231 | pubmed:language | eng | lld:pubmed |
pubmed-article:15267231 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15267231 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15267231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15267231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15267231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15267231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15267231 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15267231 | pubmed:month | Jul | lld:pubmed |
pubmed-article:15267231 | pubmed:issn | 0022-2623 | lld:pubmed |
pubmed-article:15267231 | pubmed:author | pubmed-author:WolfeMichael... | lld:pubmed |
pubmed-article:15267231 | pubmed:author | pubmed-author:DasChittaranj... | lld:pubmed |
pubmed-article:15267231 | pubmed:author | pubmed-author:BihelFrédéric... | lld:pubmed |
pubmed-article:15267231 | pubmed:author | pubmed-author:BowmanMichael... | lld:pubmed |
pubmed-article:15267231 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15267231 | pubmed:day | 29 | lld:pubmed |
pubmed-article:15267231 | pubmed:volume | 47 | lld:pubmed |
pubmed-article:15267231 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15267231 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15267231 | pubmed:pagination | 3931-3 | lld:pubmed |
pubmed-article:15267231 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:meshHeading | pubmed-meshheading:15267231... | lld:pubmed |
pubmed-article:15267231 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:15267231 | pubmed:articleTitle | Discovery of a Subnanomolar helical D-tridecapeptide inhibitor of gamma-secretase. | lld:pubmed |
pubmed-article:15267231 | pubmed:affiliation | Center for Neurologic Diseases, Harvard Medical School and Brigham & Women's Hospital, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA. | lld:pubmed |
pubmed-article:15267231 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:15267231 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:15267231 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15267231 | lld:chembl |
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